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Morphology by diagnosis
Normal bone marrow aspiration
Anemia
Iron deficiency
Megaloblastic anemia
Hemolytic anemia
General morphological BM features
Hereditary spherocytosis
Hereditary ovalocytosis
Thalassemia
Sickle cell
Cold agglutinin disease (CAD)
Aplastic anemia
Pure red cell aplasia
Congenital dyserythropoietic anemia…
Acute leukemias
Acute Lymphoblastic leukemia
B-ALL
T-ALL
Acute Myeloid Leukemias
Diagnostic tool AML WHO 2022
AML with recurrent genetic abnormalities
APL with PML-RARA
APL variant with PML-RARA
AML with Inv(16)(p13;q22) or…
AML with t(8;21)(q22;22)
AML with NPM1 and FLT3 mutation
AML with dysplastic related changes
AML NOS
AML with minimal differentiation
AML without maturation
AML with maturation
AML myelomonocytic
AML monoblastic/monocytic
Acute Erythroid Leukemia
Acute Megakaryoblastic Leukemia
Hypoplastic AML
Blastic plasmacytoid dendritic cell…
Mixed phenotype acute leukemia (MPAL)
Myelodysplastic Syndromes (MDS)
PB and BM findings of MDS WHO 2022
MDS with isolated del(5q)
MDS with mutated SF3B1 (MDS-SF3B1)
MDS-LB-SLD (MDS with low blasts; MDS…
MDS-LB-MLD (MDS with low blasts; MDS…
MDS-IB-1 (MDS with increased blasts-1)
MDS-IB-2 (MDS with increased blasts-2)
Myeloproliferative neoplasms (MPN)
PB and BM finding of MPN WHO 2022
Chronic Myeloid Leukemia (CML) BCR-ABL…
Polycythemia Vera (PV)
Essential Thrombocythemia (ET)
Primary Myelofibrosis (PMF)
Chronic neutrophilic leukemia (CNL)
idiopathic Hypereosinophilic Syndrome…
MDS / MPN
Diagnostic criteria MDS / MPN WHO 2022
MDS/MPN with neutrophilia (WHO 2016:…
Chronic Myelomonocytic Leukemia (CMML)
MDS/MPN with SF3B1 mutation and…
Different megakaryocytes
Mastocytosis
Systemic Mastocytosis (SM)
SM with an Associated Haematologic…
Lymphoid neoplasms
mature B-cell neoplasms
Chronic Lymphocytic Leukemia (CLL)
B-cell ProLymphocytic Leukemia (B-PLL)
Hairy Cell Leukemia (HCL)
Hairy Cell Leukemia-variant (HCL-v) /…
LymphoPlasmacytic Lymphoma (LPL)
Follicular Lymphoma (FL)
Mantle Cell Lymphoma (MCL)
Splenic Marginal Zone Lymphoma (SMZL)
Splenic diffuse red pulp small B-cell…
MALT lymphoma / Extranodal marginal zone…
Multiple Myeloma
Plasma Cell Leukemia (PCL)
Diffuse Large B-cell Lymphoma (DLBCL)
Burkitt Lymphoma
Richter Transformation
mature T-cell neoplasms
T-cell Large Granular Lymphocyic…
T-cell ProLymphocytic Leukemia (T-PLL)
Sézary Syndrome (SS)
Adult T-cell Lymphoma/Leukemia (ATLL)
NK-cell neoplasms
NK-cell Large Granular Lymphocyic…
Aggresive NK-cell lymphoma/leukemia
Miscellaneous
VEXAS syndrome
Osteoclasts / Osteoblasts
Gelatinous transformation
persistent polyclonal B-cell…
Thrombocytopenias
Grey platelet disease
ITP
Thrombotic microangiopathies
Pelger Huët anomaly
May Hegglin anomaly
Chediak higashi syndrome
Chanarin Dorfman syndrome
Batten’s disease (NCL-3)
Gaucher’s disease
Hemophagocytic Lympho Histiocytosis…
Alcohol abuse
Regeneration after myelosuppresive…
Infectieus diseases
Infectious mononucleosis
Parvo infection
Mycobacterium tuberculosis
Whooping cough infection
Parasitology
Malaria
differentiation Plasmodium
P. Falciparum
P. Vivax
P. Ovale
P. Malariae
P. Knowlesi
Trypanosomiasis
Leishmaniasis
Filariasis
Babesiosis
Borrelia recurrentis
Non-hematologic metastatic disease
Carcinomas
Breast cancer
Lung cancer
Adenocarcinoma lung
Small cell lung carcinoma
Squamous cell carcinoma
Prostate carcinoma
Thyroid cancer
Colorectal carcinoma
Gastric cancer
Pancreas carcinoma
Sarcomas
Osteosarcoma
Ewing sarcoma
Hodgkin lymphoma
Other malignancies
Melanoma
Seminoma
Renal cell carcinoma
Basics of Blood
Erythrocytes
Hypochromasia
Macrocytosis
Spherocytosis
Elliptocytosis
Bite cells
Echinocytes (burr cells)
Acanthocytes (spur cells)
Schistocytes (fragmentocytes)
Target cells
Teardrop cells
Sickle cell anemia
Rouleaux formation
Polychromasia
Basophilic stippling
Pappenheimer bodies
Howell Jolly bodies
Cabot rings
Malaria parasites
Erythroblasts
Granulocytes
Toxic granulation & Döhle inclusion…
Bacteria
Hypersegmentation
Hyposegmentation & degranulation
Pelger Huet
Crystals of Death
Macropolycytes
Lymphocytes
Reactive changes
Malignant changes
Monocytes
Blasts
Dysplasia
Erythropoiesis
Myelopoiesis
Megakaryopoiesis
Cell maturation
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