persistent polyclonal B-cell lymphocytosis (PPBL)

There is a chronic lymphocytosis with medium sized lymphocytes with abundant faintly basophilic cytoplasm and a variable proportion showing bi-lobed nuclei. Chromatin is a little less dense then in normal lymphocytes.
It is important to discriminate the disorder of persistent polyclonal B-cell lymphocytosis from other malignant lymphoproliferative diseases.