MDS/MPN with ringsideroblasts and thrombocytosis (MDS/MPN-RS-T)

Combined thrombocytosis (>450 x 109/L) and refractory anemia.
Bone marrow megakaryopoiesis showing morphological features which can resemble ET or PMF, erythropoiesis showing dysplastic features and >15% ring sideroblasts. Mutation of gene SF3B1 is frequently found, comutation with JAK2 V617F also.

Diagnostic criteria