Diffuse Large B-cell Lymphoma (DLBCL)

There is great morphologic variability; mediumsized blastoid lymphoid cells containing fine chromatin, 1-4 nucleoli, often scanty basophilic cytoplasm, or large cell variants with more coarse chromatin and relatively abundant cytoplasm or very large cells with rond to oval or pleomorph nuclei, resembling Hodgkin cells. Vacuolisation is often seen.