AML myelomonocytic

Acute myelomonocytic leukemia is defined by proliferation of both neutrophil and monocytic precursors. Both lineages should at least comprise >20% each. The monocytic component may be more evident in the PB bloodsmear than in the bone marrow, since differentiating promonocytes and promyelocyts can be difficult. Using flow cytometry to identify these two populations can be very helpfull.