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  myeloblasts lymphoblasts monoblasts pro erythroblasts megakaryoblasts

                            

size variable, mainly large
(13–20 µm)
variable, mainly small
(11–19 µm)
mainly large
(12–20 µm)
large
(14–20 µm)
large
(20–30 µm)

nucleus – eccentric in cell
– round to slightly oval
– chromatin fine & granular,
   evenly dispersed
– nucleoli present; 1-3
– centrally-located
– usually round,
   sometimes indented
– (very) condensed
   chromatin
– indistinct nucleoli
– centrally-located
– round ~ indented
– (coarse) reticular chromatin
– prominent nucleoli
– round
– centrally-located
– coarse reticular and
   bumpy chromatin
– 1-2 nucleoli
– round or slightly indented
– fine reticular chromatin
– 1-3 nucleoli

cytoplasm – variable in size
– moderate basophilic
– Auer rods in
   pathological blasts
– scanty
– basophilic
– never Auer rods
– abundant
– intensely basophilic to
   lighter shade of blue
– deeply basophilic – basophilic
– blebbing or budding

vacuolisation – rare – can be present
   in cytoplasm and
   sporadically in nucleus
– often present – often present
   in pathological blasts
– can be present
   in pathological blasts